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How High Blood Sugar Levels Develops from our Diet
For most people, impaired control and use of glucose starts with diets rich in sugar and/or fats. The initial impact is generally in the liver. Cells use glucose mainly through a process celled “Glycolysis”. As we grow older, often the cells of the liver become overwhelmed with glucose entering glycolysis which leads to metabolic stress, inflammation and insulin resistance. This is called ‘Glycolytic overload”. The liver starts trying to counter this by exporting excessive glucose continually. The liver also develops decreased sensitivity to insulin which normally stops it producing glucose when we eat; after meals glucose formation in the liver is not needed as glucose is being absorbed from food. Excessive fat exacerbates this decreased response to insulin. This excessive export of glucose from the liver exposes other tissues to increased levels of glucose – including muscle, fat tissue and insulin producing “beta-cells” of the pancreas. This leads to decreased insulin sensitivity of muscle and fat tissue and metabolic stress of pancreatic beta-cells. This impairs metabolic health with decrease control and balance of blood glucose and decreased insulin sensitivity. We might notice this as unusual variation of blood glucose and decreased energy.
How GlucoRegulate by GloVitality® helps
GlucoRegulate by GloVitality® supplement utilizes a fully patented, regulatory-compliant blend of trans-resveratrol and hesperetin to solve glycolytic overload at the source:
- It activates the master health protection protein Nrf2. This regulates health protective genes to counter metabolic stress, oxidative stress and decrease inflammation.
- It provides the optimum diversion for excess glucose. It smoothly diverts excess glucose away from the overloaded glycolysis into the Pentose Phosphate Pathway (PPP) which enhances protective cellular antioxidant reserve. This converts a potential energy crash into metabolic resilience.
- It normalizes gateway level entry to glucose use In muscle and fat tissue, it restores the entry of glucose into glycolysis to normal levels to relieve metabolic stress, restore normal insulin sensitivity and immunity.
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Health Risks Due to Elevated Blood Glucose Levels
Some people can often have persistently raised blood glucose levels after meals and overnight. When this happens it can increase the risk of developing decreased senstivity to insulin – a condition where the liver, muscles and fat tissues have decreased responsiveness to insulin.
Uncorrected, over the long term this can lead to serious health conditions such as…
What Makes GlucoRegulate Better?
Resveratrol has been available as a supplement for many years. Its health benefits have often been limited due to achieving only a low concentration insufficient to activate the master health protective protein, Nrf2. Its important to select trans-resveratrol and NOT cis-resveratrol (another version) which is 9-fold less effective. GloVitality scientists screened compounds to combine with trans-resveratrol to give a helping hand: to produce strong Nrf2 activation at low concentration of trans-resveratrol achieved clinically. Hesperetin uniquely does this. trans-Resveratrol and hesperetin combination in GlucoRegulate produce strong Nrf2-linked health responses whilst maintaining high safety and tolerability.
What is Resveratrol?
Resveratrol is a polyphenol compound found in various beverages and plant-based foods, most commonly from red wine and the skin of red grapes. Other sources include blueberries, cranberries, mulberries and peanuts. However, the amount of Resveratrol found in these sources is minimal, meaning a very large intake of food/drink is needed to ingest the same amount of Resveratrol found in one capsule of GlucoRegulate. trans-Resveratrol from one capsule equates to approximately one thousand times the amount in the average daily diet. It is not possible to consume this amount from the diet from grape juice as it would require 8 litres of grape juice, which would mean an excessive intake of sugar (132 grams which is 440% of daily recommended adult intake). Hence, supplements are ideal to help regulate blood glucose levels.
As well as helping to regulate blood glucose levels and improve insulin sensitivity in combination with hesperetin in GlucoRegulate, trans-Resveratrol has additional benefits such as antioxidant and anti-inflammatory effects – which are also enhanced by combination with hesperetin.
Is all trans-Resveratrol the same?
Resveratrol comes in many forms, the purest and most researched form is trans-Resveratrol. It is commonly derived from Japanese knotweed and used in capsules in the form of a powder. When supplied with a purity of at least 99%, trans-Resveratrol is a white powder and almost odourless. However, there are many supplements on the market with low purity and low quality, they appear as a brown powder with a strong distinctive odour. If the supplier is unable to provide a Certificate of Analysis from 3rd party lab tests than you should avoid that supplement. As a general rule, only consider supplements with at least 99% purity of trans-Resveratrol.
What is Hesperetin?
Hesperetin is a flavanone compound found in citrus fruits such as oranges, grapefruits, tangerines, lemons and limes. The amount found in juices of these fruits is very low. Hesperetin from one capsule equates to approximately one hundred times the amount of Hesperetin in the average daily diet, mostly from orange juice. Again, this is not possible to consume through our diet due to the excessive intake of sugar, hence supplements are ideal.
As well as helping to regulate blood glucose levels and insulin sensitivity in GlucoRegulate, hesperetin has antioxidant and anti-inflammatory effects – which are also enhanced by combination with trans-resveratrol in GlucoRegulate.
