NO MAGIC FORMULA, JUST SCIENCE!
How High Blood Sugar Levels Develops from our Diet
Methylglyoxal (MG) is formed from early stage glucose metabolism and has the effect of modifying proteins. Normal levels of MG are kept low when metabolised by the enzyme glyoxalase (Glo1).
Frequent consumption of simple sugars increases the levels of blood glucose (sugar) in the blood – referred to as hyperglycemia. This increases methylglyoxal levels in the blood which activates a health-impairing, pathogenic response linked to the development of insulin resistance and Type 2 diabetes.
In 2016, our scientists started clinical trials to develop a food supplement based on the enzyme Glo1. The optimum formulation of Glo1 inducer is trans-resveratrol and hesperetin (tRES+HESP), which has been patented. Their study found that increasing the levels of Glo1, via an oral capsule taken once a day for eight weeks, helped to correct insulin resistance, improve insulin sensitivity and decrease blood glucose levels to that of a normal healthy person.
Want to see the results of our clinical trial?
Health Risks Due to Elevated Blood Glucose Levels
Some people can often have persistently raised blood glucose levels after meals and overnight. When this happens it can increase the risk of developing insulin resistance – a condition where the liver, muscles and fat tissues have decreased responsiveness to insulin.
Uncorrected, over the long term this can lead to serious health conditions such as…
What Makes GlucoRegulate Better?
Resveratrol has been available on the market for many years, however the bio-availability (absorption by the body) of resveratrol on its own is less than 1%. What makes GlucoRegulate unique and patented is the addition of Hesperetin which is critical to increase the bioavailability of trans-Resveratrol and increase the health benefits by up to 79 times more.
What is Resveratrol?
Resveratrol is a polyphenol compound found in various beverages and plant-based foods, most commonly from red wine and the skin of red grapes. Other sources include blueberries, cranberries, mulberries and peanuts. However, the amount of Resveratrol found in these sources is minimal, meaning a very large intake of food/drink is needed to ingest the same amount of Resveratrol found in one capsule of GlucoRegulate. Resveratrol from one capsule equates to approximately one thousand times the amount of Resveratrol in the average daily diet. It is not possible to consume this amount from the diet as grape juice as it would require 8 litres of grape juice, which would mean an excessive intake of sugar (132 grams which is 440% of daily recommended adult intake). Hence, supplements are ideal to help regulate blood glucose levels.
As well as helping to regulate blood glucose levels, Resveratrol has additional benefits such as it may; reduce the risk of heart disease, reduce cholesterol levels, has anticancer, antioxidant and anti-inflammatory effects.
Is all Resveratrol the same?
Resveratrol comes in many forms, the purest and most researched form is trans-Resveratrol. It is commonly derived from Japanese knotweed and used in capsules in the form of a powder. When supplied with a purity of at least 99%, trans-Resveratrol is a white powder and almost odourless. However, there are many supplements on the market with low purity and low quality, they appear as a brown powder with a strong distinctive odour. If the supplier is unable to provide a Certificate of Analysis from 3rd party lab tests than you should avoid that supplement. As a general rule, only consider supplements with at least 99% purity of trans-Resveratrol.
What is Hesperetin?
Hesperetin is a flavanone compound found in citrus fruits such as oranges, grapefruits, tangerines, lemons and limes. The mount found in juices of these fruits is very low. Hesperetin from one capsule equates to approximately one hundred times the amount of Hesperetin in the average daily diet, mostly from orange juice. Again, this is not possible to consume through our diet due to the excessive intake of sugar, hence supplements are ideal.
As well as helping to regulate blood glucose levels, Hesperetin has antioxidant and anti-inflammatory effects. It also facilitates the uptake of Resveratrol into the body, by up to 79 times than Resveratrol on its own, so increasing the health beneficial effects.
